ASP.NET Uploaded File

I have an ASP.NET web application that uses jQuery on client side.
On one of the web forms I have a bunch of controls to fill, and an upload control.
User can run upload while filling other entries on the form.
When user saves the form, all data including file is stored into database .
The question is what to do with uploaded file while user fills the form?
I have two possible solutions, but don’t know which of them is more optimal

Edit a line in a file depending on user’s input | Python

I’m working on a contact book application to improve my python skill, so far I’ve created functions to add new contact, view existing contact, but I’m stuck on a function to edit them, I don’t know how to tackle this task (note that editing and adding information is based on user input), currently the only information this application is recording are name, phone number and/or email (if user entered an email).