How do you force Visual Studio to regenerate the .designer files for aspx/ascx files?

Sometimes when I’m editing page or control the .designer files stop being updated with the new controls I’m putting on the page. I’m not sure what’s causing this to happen, but I’m wondering if there’s any way of forcing Visual Studio to regenerate the .designer file. I’m using Visual Studio 2008

Why the Ajax script is not running on IIS 7.5 Win 2008 R2 server?

I have a web app that works fine on VS 2013 on my development server, but once I published it on the IIS 7.5 2008 R2 server the Ajax scripts, located on my custom script file, don’t work anymore, although the other JQuery scripts that do not call Ajax do work properly. Is there anything else that needs to be done in order to have ajax working in the server? I’ve read some posts about, but couldn’t find an answer yet. I’ve limited experience in IIS and Ajax.